The Pharmaceutical Chemistry Department is divided into two sections; Medicinal Chemistry and Analytical Chemistry.
Medicinal Chemistry is an interrelated discipline combining synthetic organic chemistry, pharmacology, microbiology, biochemistry, physical and computational chemistry. It is concerned with the drug discovery and development process, starting from target identification, finding a lead compound, structure-activity relationship investigations to lead optimization, using different technologies such as In-silico screening and high throughput screening. Also, it involves the study of the pharmacokinetic/ pharmacodynamic properties of different pharmaceutical active agents, their synthetic strategies, and the structure activity relationships of these drugs.
Pharmaceutical Analytical Chemistry
Pharmaceutical analytical chemistry comprises a branch of chemistry that deals with identification and determination of drug concentration in different pharmaceutical dosage forms as well as in biological fluids such as plasma, serum and urine, and, deals with drug and elemental analysis in environmental samples. It is considered the backbone of pharmaceutical industry as it helps quality control units in analysis of raw materials, intermediate products and final drug dosage forms to assure that the drug product is safe and effective.
The chemical methods of analysis used include titrimetric analysis (acid – base reactions, precipitation reactions or complexation reactions), electrochemical analysis (redox reactions, potentiometry, and conductometry), and finally, instrumental analysis as spectroscopy and chromatography.